Advances in Visualization Tools for Phylogenomic and Phylodynamic Studies of Viral Diseases KU Leuven
Viral genetic variation accounts for a third of variability in HIV-1 set-point viral load in Europe Institute of Tropical Medicine
HIV-1 set-point viral load-the approximately stable value of viraemia in the first years of chronic infection-is a strong predictor of clinical outcome and is highly variable across infected individuals. To better understand HIV-1 pathogenesis and the evolution of the viral population, we must quantify the heritability of set-point viral load, which is the fraction of variation in this phenotype attributable to viral genetic variation. ...