Projects
Protective potential of obesity against critical illness induced muscle wasting KU Leuven
Kritieke ziekte is elke acute medische conditie waarvoor de patiënt intensieve medische ondersteuning nodig heeft van vitale organen om te kunnen overleven. Ondanks vooruitgang in de intensieve geneeskunde, heeft ongeveer 30% van de kritiek zieke patïenten langdurig nood aan intensieve zorgen. Deze verlengde vorm van kirtieke ziekte gaat samen met hypercatabolisme, spierverlies en spierzwakte, wat ook kan zorgen voor verlengde nood aan ...
The role of adipose tissue in ICU-acquired weakness KU Leuven
Prolonged critically ill patients frequently develop muscle wasting and weakness of limb and respiratory muscles, termed critical illness-induced or intensive care unit (ICU)-acquired weakness. Mechanisms underlying this debilitating condition are complex, affecting both muscles and nerves. Whereas hypercatabolism in these patients induces loss of muscle mass, counterintuitively, adipose tissue is preserved or even increased during prolonged ...
Non-invasive imaging to study atrial remodeling underlying the progressive nature of atrial fibrillation. KU Leuven
Inverse relationship between bone mass and fat mass: effects of steroid metabolism in the fatty tissue and fetal imprinting Ghent University
Starting from previous observations in clinical studies of male osteoporosis of our research group, in which an inverse relationship was found between fat mass and bone mass, the present project wishes to examine the effects of adipose tissue on the bone, by means of further animal experimental work. The mechanism of this inverse relationship is not completely known, where two hypotheses will be investigated. (1) The inverse relationship ...