Inter-organelle communication through membrane contact sites in oncology and neurodegenerative diseases (InterAction) KU Leuven
Laboratory of Cellular Transport Systems, Laboratory of Membrane Trafficking (VIB-KU Leuven), Laboratory of Cell Death Research & Therapy (VIB-KU Leuven), Laboratory of Lipid Metabolism and Cancer
‘Membrane contact sites’ (MCSs) between organelles within a eukaryotic cell provide structural integrity and promote organelle homeostasis by facilitating intracellular signalling, exchange of metabolites, lipid metabolism and membrane dynamics. Cataloguing MCSs revolutionized our understanding of the structural organization of a eukaryotic cell, but the functional role of MCSs is only gradually emerging. Moreover, alterations of the molecular ...