Production of immunogenic tumor lysate loaded mesoporous silica nanoparticles as anti-cancer vaccine KU Leuven
With cancer being a leading cause of mortality, immunotherapy is emerging as an innovative procedure to control the disease. It is a fast evolving complex field aiming to stimulate components of the immune system against tumor cells. One of these approaches is active specific immunotherapy based on the injection of autologous mature dendritic cells loaded with autologous tumor lysate. Proof-of-principle studies have shown that these vaccines ...