Patents

This invention relates to a method and a custom device for automatically digitizing X ray photographs.

The present disclosure relates to the anticonvulsant activity of S. miltiorrhiza and tanshinones, and the use of compounds from S. miltiorrhiza as anticonvulsant agents for the treament of epilepsy and neurological disorders characterized by seizures.

Manufacturing a semiconductor device involves forming (200) a sacrificial layer where a micro cavity is to be located, forming (210) a metal layer of thickness greater than 1 micron over the sacrificial layer, forming (220) a porous layer from the metal layer, the porous layer having pores of length greater than ten times their breadth, and having a breadth in the range 10nm -500 nanometers. The pores can be created by anodising, electrodeposition or dealloying. Then the sacrificial layer can be removed (230) through the porous layer, to form the micro cavity, and pores can be sealed (240). ...

A valve system for a mouth mask is disclosed. The valve system comprises a first rigid member and a second rigid member, having at least partially mated surfaces to closely fit to one another, a flexible member and a tightening means. The first rigid member and the second rigid member, the flexible member and the tightening means are configured so that the flexible member can be positioned between the first rigid member and the second rigid member so that the flexible member, when the tightening means is in position, is centrally tightened between the first rigid member and the second rigid ...

This document relates to methods and materials for detecting mutations that can be linked to dementia. For example, methods and materials for detecting one or more mutations within PGRN nucleic acid are provided. This document also provides methods and materials for detecting the level of progranulin expression. In addition, this document relates to methods and materials for treating mammals having a neurodegenerative disorder (e.g., dementia). For example, methods and materials for increasing PGRN polypeptide levels in mammals are provided, as are methods and materials for identifying agents ...

This document relates to methods and materials for detecting mutations that can be linked to dementia. For example, methods and materials for detecting one or more mutations within PGRN nucleic acid are provided. This document also provides methods and materials for detecting the level of progranulin expression. In addition, this document relates to methods and materials for treating mammals having a neurodegenerative disorder (e.g., dementia). For example, methods and materials for increasing PGRN polypeptide levels in mammals are provided, as are methods and materials for identifying agents ...

This document relates to methods and materials for detecting mutations that can be linked to dementia. For example, methods and materials for detecting one or more mutations within PGRN nucleic acid are provided. This document also provides methods and materials for detecting the level of progranulin expression. In addition, this document relates to methods and materials for treating mammals having a neurodegenerative disorder (e.g., dementia). For example, methods and materials for increasing PGRN polypeptide levels in mammals are provided, as are methods and materials for identifying agents ...

The present invention relates to a reservoir computing device comprising a cascade of at least two reservoir computing blocks, each reservoir computing block comprising - summing means for making a sum of a block input signal and a delayed signal output by the reservoir computing block, - a digital filter structure arranged for applying a non-linear function to said sum and for adding to a non-linear function output a filtered version of a preceding non-linear function output, yielding a digital filter structure output signal, - a delay line structure arranged for receiving as input the ...

The present invention relates to a novel compound, to a pharmaceutically acceptable salt or optical isomer thereof, to a method for preparing same, and to a pharmaceutical composition for the prevention or treatment of viral diseases containing same as an active ingredient. The novel compound according to the present invention not only has low cytotoxicity but also has excellent antiviral activity against picornavirus such as coxsackievirus, enterovirus, echovirus, poliovirus and rhinovirus, and thus can be effectively used as a pharmaceutical composition for the prevention or treatment of ...

The present invention relates to 1,3-dioxoindene derivatives, pharmaceutically acceptable salts or optical isomers thereof, a preparation method for same, and a pharmaceutical composition containing same as an active ingredient with antiviral activity. The 1,3-dioxoindene derivatives of formula (1) according to the present invention have low cyto-toxicity, and can also demonstrate utility as pharmaceutical compositions for preventing or treating viral diseases such as:; polio, viral paralysis, acute hemorrhagic conjunctivitis, viral meningitis, hand-foot-mouth disease, blistering diseases, ...