The potential of Lactobacillus exopolysaccharides and glycoproteins as safe vaccine adjuvants. University of Antwerp
The working mechanism of a new class of adjuvant, the Layered Double Hydroxide (LDH) family. Ghent University
This interdisciplinary project combines key aspects of chemistry and immunology to predict which members of a new class of adjuvants, the Layered double hydroxide family (LDH), induce a better cellular and/or humoral immune response than the common used adjuvant alum. Besides, we will unravel their cellular and molecular mechanism of action and their applicability in an influenza infection model.
Dendritic cells as a potential target for the development of an atherosclerosis vaccine. University of Antwerp
A novel, DNA-based, live-attenuated vaccine for the yellow fever virus and other medically important flaviviruses. KU Leuven
Many vaccines are still composed of a purified antigen or a whole, inactivated pathogen combined with adjuvants. Alternatively, as is the case for yellow fever virus (YFV), measles, mumps and rubella, purified, live-attenuated virus vaccines are available. Both types of vaccines are expensive to produce and require a cold distribution chain from manufacturer to patient, which is in particular hard to achieve in resource-poor or remote ...
Role of dendritic cells in Th1/Th17-mediated immune diseases. University of Antwerp
ReLACT: Intranasal probiotics against respiratory viral infections. University of Antwerp
The aim of this Concept TT is to obtain a technical proof of concept that shows the potential of polymer-lipid amphiphiles as carrier for lymph node-targeted delivery of small molecule immuno-modulators. Ultimately, the research results will be used to support a patent application.