Publications
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Six years progression of exercise capacity in subjects with mild to moderate airflow obstruction, smoking and never smoking controls Ghent University KU Leuven
Background Exercise capacity is an important feature in patients with COPD. Its impairment drives disability and dependency for daily activities performance. This study evaluated the six years change in exercise capacity in subjects with airflow obstruction and compared this to subjects without airflow obstruction, with and without a smoking history. Methods Cardiopulmonary exercise tests (CPET) were repeatedly performed during a six years ...
Chemical stabilization of Cd-contaminated soil using biochar Ghent University
Partial homologies between sleep states in lizards, mammals, and birds suggest a complex evolution of sleep states in amniotes Ghent University University of Antwerp
It is crucial to determine whether rapid eye movement (REM) sleep and slow-wave sleep (SWS) (or non-REM sleep), identified in most mammals and birds, also exist in lizards, as they share a common ancestor with these groups. Recently, a study in the bearded dragon (P. vitticeps) reported states analogous to REM and SWS alternating in a surprisingly regular 80-s period, suggesting a common origin of the two sleep states across amniotes. We first ...
Meeting report: Cellular gateways : expanding the role of endocytosis in plant development Ghent University
The occasion of The Company of Biologists' workshop 'Cellular gateways: expanding the role of endocytosis in plant development' on 22-25 April 2018, at Wiston House, an Elizabethan mansion in West Sussex, England, witnessed stimulating and lively discussions on the mechanism and functions of endocytosis in plant cells. The workshop was organized by Jenny Russinova, Daniel Van Damme (both VIB/University of Ghent, Belgium) and Takashi Ueda ...
Methodologies to investigate intracellular barriers for nucleic acid delivery in non-viral gene therapy Ghent University
The two water worlds hypothesis : addressing multiple working hypotheses and proposing a way forward Ghent University
Recent studies using water isotopes have shown that trees and streams appear to return distinct water pools to the hydrosphere. Cryogenically extracted plant and soil water isotopic signatures diverge from the meteoric water lines, suggesting that plants would preferentially use bound soil water, while mobile soil water that infiltrates the soil recharges groundwater and feeds streamflow all plots on meteoric water lines. These findings have ...
Endosomal size and membrane leakiness influence proton sponge-based rupture of endosomal vesicles Ghent University
In gene therapy, endosomal escape represents a major bottleneck since nanoparticles often remain entrapped inside endosomes and are trafficked toward the lysosomes for degradation. A detailed understanding of the endosomal barrier would be beneficial for developing rational strategies to improve transfection and endosomal escape. By visualizing individual endosomal escape events in live cells, we obtain insight into mechanistic factors that ...