Projects
Beam steering and control of large area ultrasound actuator arrays for haptic perception KU Leuven
Traditional microphone units focus on human perceptible sound waves (between 20 Hz and 20 kHz). Acoustic development also focuses on ultrasound, compromising the frequencies above the detection limit of the human ear (from 20 kHz to several GHz). These sound waves can be used for a wide variety of applications, including medical imaging, therapeutic treatment, non-destructive testing and position localization of objects. Nowadays, ultrasonic ...
Ultrasound assisted crystallisation in microreactors KU Leuven
This research project studied the use of ultrasound in cooling crystallization as an alternative seeding and particle engineering technique. To accomplish this goal, the fundamentals of the cavitation phenomena were first studied to identify the operating conditions suitable for crystallization. Next, the implementation, operation and settings of the ultrasonic field during cooling crystallization were optimized. Finally, possible reactor ...
Mechanical high intensity focused ultrasound (mHIFU): exploring the synergistic effects between killing tumor cells and inducing antitumor immunity in vivo. Ghent University
The discovery that certain types of “classical” cancer therapies, including specific chemotherapeutic
drugs and radiotherapy regimens were able to kill tumor cells in such a way that they alert the
patient’s immune response, revolutionized our view on the interaction of these therapies with the
immune system. This so-called immunogenic cell death (ICD) brings about an army of immune cells
that can specifically ...
Experimentally validated computational pipeline of ultrasound propagation and neuron-coupling for non-invasive peripheral nervous system stimulation Ghent University
Ultrasound has gained attention in the last decade for the application of high-precision non-invasive neuromodulation. In particular, ultrasound can reach deep targets with millimeter precision and without surgery, in contrast to existing electrostimulation technologies. However, limited understanding of the mechanism by which ultrasound interacts with neurons has hampered systematic neural engineering studies, that aim to design ultrasound ...
Exploiting ultrasound resonance to intensify photochemical reactors KU Leuven
Small-scale flow reactors for photochemistry support the shift in
chemical manufacture towards green and sustainable processes
based on renewable energy sources. However, the industrial
application of these small-scale flow reactors is significantly limited
by their currently achieved throughput and productivity. This project
aims to overcome these productivity limitations by exploiting the
...Large Area Ultrasound Actuator Arrays for Haptic Perception KU Leuven
Traditional microphone units focus on human perceptible sound waves (between 20 Hz and 20 kHz). Acoustic development also focuses on ultrasound, compromising the frequencies above the detection limit of the human ear (from 20 kHz to several GHz). These sound waves can be used for a wide variety of applications, including medical imaging, therapeutic treatment, non-destructive testing and position localization of objects. Nowadays, ultrasonic ...
Wireless Powering of Brain Implants with Ultrasound KU Leuven
The miniaturization revolution that we see in communication and computing is also occurring in the medical diagnostic and therapeutic world. In recent years there has been a rapid emergence of advanced (wearable) medical devices that bring high quality medically relevant diagnostics in an increasingly convenient format at ever lower costs. More recently, there has been a shift toward advanced implantable devices that require minimally ...
Investigating the neuromodulatory effect of focused ultrasound in the human brain. Ghent University
Brain disorders affect one in four people and treatment is often ineffective or invasive. It is an aspiration of medicine and neuroscience to non-invasively modulate any given region of the brain with high precision. Ultrasonic waves can be safely focused through the human skull and are able to modulate neuronal activity at millimeter resolution. The currently available ultrasonic
neuromodulation protocols for human applications have ...
Reconstruction of acoustic tissue properties for ultrasound tissue characterization KU Leuven
Ultrasound imaging is an indispensable tool in medical diagnostics and offers several advantages over other imaging techniques. During last decades, ultrasound technology has achieved significant progress leading to improved image quality. However, conventional ultrasound envelope-detected images remain qualitative in nature and lack quantitative information on the tissue state and pathology. Therefore, there has been an increased interest in ...