The molecular signature of cross-modal brain plasticity in the mouse: development and application of a targeted plasma membrane proteomics approach KU Leuven
When a sensory system fails, the deprived cortical neurons can be recruited by the remaining senses and in parallel, sensory processing in the spared modalities will be refined to facilitate compensation for the sensory loss. Recently, our research group successfully introduced monocular enucleation (ME) as a model to investigate these so-called ‘cross-modal plasticity mechanisms’ in mouse visual system. After all, the contralateral visual ...