Immune profiling and the role of monocyte/macrophage populations in primary sclerosing cholangitis and related ulcerative colitis Ghent University
Primary sclerosing cholangitis (PSC) is a chronic idiopathic cholestatic liver disease characterized by biliary inflammation and stricture-formation and hepatic fibrosis/cirrhosis. Recurrent episodes of intestinal inflammation, mostly corresponding to ulcerative colitis (UC), are frequently observed. The etiopathogenesis of the disease and the driving force behind the concomitant presentation have not been elucidated but both are classified ...