Publications
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MALrisk: a machine-learning–based tool to predict imported malaria in returned travellers with fever Institute of Tropical Medicine
Background: Early diagnosis is key to reducing the morbi-mortality associated with P. falciparum malaria among international travellers. However, access to microbiological tests can be challenging for some healthcare settings. Artificial Intelligence could improve the management of febrile travellers.
Methods:Data from a multicentric prospective study of febrile travellers were obtained to build a machine-learning model to predict ...
Methods:Data from a multicentric prospective study of febrile travellers were obtained to build a machine-learning model to predict ...
Clostridium difficile infection in returning travellers Institute of Tropical Medicine
Background There is increasing recognition of the contribution of community-acquired cases to the global burden of Clostridium difficile infection (CDI). The epidemiology of CDI among international travellers is poorly understood, and factors associated with international travel, such as antibiotic use and changes in gut microbiota, could potentially put travellers at higher risk.
Methods We summarized demographic, travel-associated ...
Challenges and risks for older travellers with multimorbidity: focus on pharmacotherapy Ghent University
Schistosoma real-time PCR as diagnostic tool for international travellers and migrants Institute of Tropical Medicine
Objective: To evaluate the use of a genus-specific PCR that combines high sensitivity with the detection of different Schistosoma species for diagnosis in international travellers and migrants in comparison to standard microscopy. Methods and results: The genus-specific real-time PCR was developed to target the 28S ribosomal RNA gene of the major human Schistosoma species. It was validated for analytical specificity and reproducibility and ...
Schistosomiasis in travellers and migrants Institute of Tropical Medicine
Schistosomiasis is a tropical parasitic disease caused by blood-dwelling fluke worms of the genus Schistosoma whose infective stages, the cercariae, are amplified through mollusks acting as intermediate hosts. People are infected when exposed to fresh water containing cercariae that penetrate the skin. There are however considerable differences in intensity of infection and morbidity, depending on the pattern of exposure and the infective ...
A simple and fast method to exclude high Plasmodium falciparum parasitaemia in travellers with imported malaria Institute of Tropical Medicine
BACKGROUND: Counts of malaria parasites in peripheral blood are important to assess severity of Plasmodium falciparum malaria. Thin and thick smears are routinely used for this purpose. METHODS: In this study the Binax NOW(R) Malaria Test, an easy-to-perform rapid diagnostic test, with Histidine Rich Protein-2 (HRP-2) and aldolase as diagnostic markers, was used for semi-quantitative assessment of parasitaemia of P. faciparum. RESULTS: In 257 ...