Projects
Towards precision medicine for Dravet syndrome using personalized zebrafish disease models KU Leuven
Discovery of therapeutic targets and precision therapies for Dravet syndrome using a zebrafish disease model KU Leuven
Despite the availability of numerous antiseizure medications, about 30% of epilepsy patients still suffer from seizures due to drug-resistant epilepsy. Hence, we need to think beyond symptomatic treatment and develop precision therapies (i.e., anti-epileptogenic therapies and disease-modifying agents) that target hub genes and key pathways within epileptogenesis, the gradual process by which a brain develops epilepsy. It is thus essential to ...
Point of care gathering and real-time utilization of smartphone generated movement traces of patients for infectious disease containment in the community. KU Leuven
In this PhD thesis, we applied different methods in clinical and epidemiological studies to understand the factors that contributed to respiratory pathogen transmission. These insights could, in turn, improve pathogen surveillance and interruption of transmission.
In one chapter, we compared SARS-CoV-2 shedding in different respiratory samples and analytical tests – nasopharyngeal (NP) quantitative polymerase chain reaction ...