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When to start dialysis in patients with acute kidney injury? : when semantics and logic become entangled with expectations and beliefs Ghent University
Earlier initiation of dialysis may have a beneficial impact on survival of critically ill patients with acute kidney injury (AKI). A retrospective analysis in the previous issue of Critical Care showed that early initiation of renal replacement therapy (RRT), as defined by RIFLE criteria, was not associated with a reduction in hospital mortality. The retrospective character of many studies describing the results of early RRT initiation and the ...
High-dose folic acid pretreatment blunts cardiac dysfunction during ischemia coupled to maintenance of high-energy phosphates and reduces postreperfusion injury University of Antwerp
Toxic nephropathy due to drugs and poisons KU Leuven
Drug-induced acute renal failure (ARF) is increasingly encountered, especially in hospitalized patients as a result of a more aggressive diagnostic and therapeutic measures in an ageing and multimedicated patient population that is increasingly vulnerable. Potentially nephrotoxic drugs include nonsteroidal antiinflammatory drugs, radiocontrast agents, antimicrobial, and anesthetic agents. Endogenous compounds such as myoglobin and hemoglobin may ...
Toxic hepatitis due to a food supplement University of Antwerp
Background/aims: Herbal products are increasingly used in modern medicine for numerous indications. They are not considered as drugs and thus often not linked to side effects. Material: A 77-year-old patient presented with silent icterus and biochemical evidence of hepatocellular damage. Because of dyslipidaemia, he was recently prescribed Controchol (R), a food supplement containing red yeast and green tea extracts. Results: Liver biopsy showed ...
Toxic exposure to caustics and respiratory irritants Ghent University
A dynamic logic of interrogative inquiry Vrije Universiteit Brussel
We propose a dynamic-epistemic analysis of the different epistemic operations constitutive of the process of interrogative inquiry, as described by Hintikka’s Interrogative Model of Inquiry (IMI). We develop a dynamic logic of questions for representing interrogative steps, based on Hintikka’s treatment of questions in the IMI, along with a dynamic logic of inferences for representing deductive steps, based on the tableau method. We then merge ...
The association between urinary kidney injury molecule 1 and urinary cadmium in elderly during long-term, low-dose cadmium exposure: a pilot study Hasselt University KU Leuven
Background: Urinary kidney injury molecule 1 is a recently discovered early biomarker for renal damage that has been proven to be correlated to urinary cadmium in rats. However, so far the association between urinary cadmium and kidney injury molecule 1 in humans after long-term, low-dose cadmium exposure has not been studied. Methods: We collected urine and blood samples from 153 non-smoking men and women aged 60+, living in an area with ...