Structural and functional insights into the role of Themis1 and Themis2 in inflammation. Ghent University
Our immune systems are sophisticated defence mechanisms which identify invading pathogens and coordinate their removal. Specialised cells known as T and B lymphocytes are key effectors of the adaptive immune response. Lymphocyte development is tightly controlled to prevent the expansion of destructive, self-reactive T and B cells and the development of autoimmune diseases. Themis, a recently described T cell specific protein, is a key ...