Projects
Digital radiation therapy patient. KU Leuven
The past decade has seen a revolution in radiation therapy technology, offering exceptional flexibility in dose delivery. Image guidance during treatment ensures a reliable targeting of the dose to the tumor. This has created the possibility to irradiate the tumor with a high dose with minimal exposure of surrounding tissue. Thus an improvement in tumor control is no longer invariably associated with an increase in radiation-induced ...
Molecular and Cellular Basis for Beta Cell Therapy in Diabetes Vrije Universiteit Brussel
BAPTON - Biology Adaptive for Proton Therapy in Oesophageal caNcer KU Leuven
More than half of the patients treated for cancer receive external Beam Radiation Therapy (EBRT) during the course of their disease. EBRT is typically characterized by highly standardized protocols and relies on the precise daily delivery of high energy X-rays combined with volumetric imaging tools. In order to further improve cancer care in Belgium, the UZ Leuven and the Cliniques Universitaires Saint-Luc have recently built in partnership ...
Role of photodynamic therapy in the prevention of intimal hyperplasia KU Leuven
Role of photodynamic therapy in the prevention of intimal hyperplasia.
Endovascular treatment of symptomatic atherosclerotic peripheral artery disease (PAD) is recommended as the primary revascularization strategy in many clinical and anatomic scenarios. Although percutaneous transluminal angioplasty (PTA) has a high initial success rate, restenosis remains the Achilles heel. Restenosis rates up to 60% are reported. Restenosis has a ...
Cognitive Functional Therapy in nurses with persistent low back pain: an intervention based on an individualised multidimensional evaluation KU Leuven
Nurses perform essential healthcare tasks within our healthcare system and adequate nursing health is crucial for the provision of effective, empathic and efficient health care. However, occupational Low Back Pain (LBP) is very common among nurses. Lifetime prevalence ranges from 35 to 84% and annual prevalence is approximately 70%. LBP is worldwide the leading cause of disability and has a significant personal, social and economic impact. ...
Strategic Research Programme: Cancer Cell Targeting in Myeloma and Melanoma (MyMe) Vrije Universiteit Brussel
Strategic Research Programme: Molecular Imaging and targeting of macrophages in Inflammation (ITARMI) Vrije Universiteit Brussel
Local and systemic immune interactions in malignant gliomas KU Leuven
Glioblastoma (GBM), the most frequent primary intrinsic brain tumor, is without any doubt one of the most devastating diseases known to mankind. GBM are currently being treated with neurosurgical resection followed by radio- and chemotherapy. However, despite this treatment, prognosis for these patients is grim with a median survival of only 15 months and less than 20% 3-year survival rates. Already at diagnosis, GBM cells are infiltrating ...
Development of Artificial Genetic Systems for Therapeutic Applications KU Leuven
Deoxyribonucleic acid (DNA) and ribonucleic acid (RNA) are among the most remarkable biomolecules occurring in nature, since they store and transfer all genetic information using only four letters (G, C, A & T or U). In the last 60 years, since the discovery of the structure of nucleic acids, numerous chemically modified nucleosides and nucleotides have been produced and incorporated into oligomeric sequences either by chemical or ...