TRP - Tackling the Roots of Pain KU Leuven
TRPLe: TRP Research Platform Leuven. KU Leuven
A TRiP to the dorsal root ganglia: Unraveling the molecular characterization of the still neglected satellite glial cells. KU Leuven
Characterization of Transient Receptor Potential (TRP) in human endometrium: in health and disease. KU Leuven
In the proposed research project we aim to provide insights into the functional role of mechanosensitive ion channels (focusing on Piezo 1, Piezo 2, TRPV4, TRPC1 and TRPC6) in the process of prostaglandin E2 (PGE2) release and production required for decidualization and embryo implantation. Interestingly, preliminary data obtained via quantitative RT-PCR on endometrium of fertile mothers showed increased expression levels of specific ...
Exploring the neuro-immune mechanisms underlying nasal hyperreactivity in rhinitis and rhinosinusitis KU Leuven
Rhinitis can present with nasal obstruction, nasal discharge, itch, or sneezing. In case of involvement of the paranasal sinuses (i.e. rhinosinusitis), facial pain or loss of smell is possible as well. Several endotypes of rhinitis and rhinosinusitis are known, such as type 1 or type 2 inflammation.
Allergic rhinitis (AR) and chronic rhinosinusitis with nasal polyps (CRSwNP) are both characterized by a mainly type 2 inflammation in the ...