Projects
Modeling and experimental validation of a gliding arc discharge: Comparison of a classical and a plasmatron gliding arc. University of Antwerp
A comparative clinical study of a stool-based versus a blood-based screening test for earlydetection of CRC KU Leuven
Colorectal cancer (CRC) is the third most common cancer worldwide and the second leading cause of cancer deaths in Europe and USA. Its incidence and difficult early-diagnosis make CRC a primary focus in the oncology community. Although colonoscopy is currently the most reliable clinical tool for precise detection of CRC, the invasive nature and the incurred cost have hampered the wide application of this procedure. On the other hand, the ...
MIMICRY - Modulating Immunity and the Microbiome for effective CRC. University of Antwerp
Modeling how pre-existing TCR clones affect vaccine-induced T-cell responses (CELLULO-EPI-BASE). University of Antwerp
Characterize specific human TCRs via TCR Seq including both NGS protocols and in silico analysis and in vitro experimental assays for T cells stimulations with tumor associated and viral antigens pools, with the final aim of TCR-T cells development. University of Antwerp
Oncoproteomics and 3D culture as tools to understand and prevent CRC metastasis KU Leuven
Cancer metastasis is the main cause of cancer associated death, the dissemination and spreading of tumoral cells from its original niche makes treatment and eradication of the malignancy almost impossible. We want to gain further insights into colorectal cancer (CRC) metastasis and this way find new diagnostic tools that allow for the early detection of CRC tumours before they have the chance to colonize other tissues. We will evaluate the ...
Optimizing a high throughput TCR-epitope recognition tool to characterize microbiome specific TCR interactions in colorectal cancer KU Leuven
Neuro-immune crosstalk favouring CRC progression and dissemination KU Leuven
Colorectal cancer (CRC) accounts for approximately 10% of all annually diagnosed cancers and cancer-related deaths worldwide. Nowadays, with continuing diagnostic progress also in developing countries, the incidence of CRC worldwide is predicted to increase to 2·5 million new cases in 2035. Furthermore, although innovative technologies have had a significant impact on the diagnosis and therapy of CRC, patients with advanced disease still have ...