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Effect of time since death on multipathogen molecular test results of postmortem specimens collected using minimally invasive tissue sampling techniques Institute of Tropical Medicine
BACKGROUND: We used postmortem minimally invasive tissue sampling (MITS) to assess the effect of time since death on molecular detection of pathogens among respiratory illness-associated deaths.
METHODS: Samples were collected from 20 deceased children (aged 1-59 months) hospitalized with respiratory illness from May 2018 through February 2019. Serial lung and/or liver and blood samples were collected using MITS starting soon after ...
Acknowledging Tissue Donation: Human Cadaveric Specimens in Musculoskeletal Research Hasselt University
Human cadaveric specimens are an important resource for research, particularly in biomechanical studies, but their use also raises ethical questions and cannot simply be taken for granted. It was asked how much information authors publishing musculoskeletal research actually give about such specimens and about how they were acquired. The aim was to formulate recommendations on how this reporting might be improved. Relevant articles published ...
The simulation of terrible triad injuries in fresh-frozen human cadaveric specimens with intact soft tissue envelope KU Leuven
INTRODUCTION: The aim of the present study was to develop a technical process to reproducibly generate terrible triad injuries (TTI) in fresh-frozen human cadaveric specimens, while leaving the skin intact. Such "pre-fractured" specimens, used for scientific analysis and for surgical education, might help to improve current treatment, which is complex and prone to complications. MATERIALS AND METHODS: To induce the desired fractures, a ...
Primary culture of Mycobacterium ulcerans from human tissue specimens after storage in semisolid transport medium Institute of Tropical Medicine Ghent University
Rates of MAGE-A3 and PRALE expressing tumors in FFPE tissue specimens from bladder cancer patients: potential targets for antigen-specific cancer immunoptherapeutics KU Leuven
INTRODUCTION: Antigen-specific active immunotherapy is an investigational therapeutic approach of potential interest for bladder cancer regardless of disease stage. Clinical development of antigen-specific immunotherapeutics against bladder cancer must be preceded by assessment of the expression of relevant genes in bladder tumors. The objectives of this study (NCT01706185) were to assess the rate of expression of the MAGE-A3 and PRAME genes in ...
An investigation of the prevalence of Oral and Oropharyngeal Human Papillomavirus in selected South African population groups and tissue specimens University of Antwerp
abstract not available
Agreement on endoscopic ultrasonography-guided tissue specimens: Comparing a 20-G fine-needle biopsy to a 25-G fine-needle aspiration needle among academic and non-academic pathologists KU Leuven
BACKGROUND AND AIM: A recently carried out randomized controlled trial showed the benefit of a novel 20-G fine-needle biopsy (FNB) over a 25-G fine-needle aspiration (FNA) needle. The current study evaluated the reproducibility of these findings among expert academic and non-academic pathologists. METHODS: This study was a side-study of the ASPRO (ASpiration versus PROcore) study. Five centers retrieved 74 (59%) consecutive FNB and 51 (41%) FNA ...
Expert opinion on NSCLC small specimen biomarker testing - Part 1: Tissue collection and management KU Leuven
Biomarker testing is crucial for treatment selection in advanced non-small cell lung cancer (NSCLC). However, the quantity of available tissue often presents a key constraint for patients with advanced disease, where minimally invasive tissue biopsy typically returns small samples. In Part 1 of this two-part series, we summarise evidence-based recommendations relating to small sample processing for patients with NSCLC. Generally, tissue biopsy ...