Publications
INHIBITION OF HISTONE DEACETYTASE 6 (HDAC6) AS A THERAPEUTIC STRATEGY IN CHEMOTHERAPY-INDUCED PERIPHERAL NEUROPATHIES KU Leuven
Emerging drugs and indications for cardio-metabolic disorders in people with severe mental illness KU Leuven
Adult stem cells and skeletal muscle regeneration KU Leuven
PET imaging of TSPO in a rat model of local neuroinflammation induced by intracerebral injection of lipopolysaccharide KU Leuven
Inhibitory effect of dietary capsaicin on liver fibrosis in mice Vrije Universiteit Brussel
SCOPE:: Virtually all chronic liver injuries result in the activation of hepatic stellate cells (HSCs). In their activated state, these cells are the main collagen-producing cells implicated in liver fibrosis. Capsaicin, the active compound of chili peppers, can modulate the activation and migration of HSCs in vitro. Here, we evaluated the potential protective and prophylactic effects of capsaicin related to cholestatic and ...
Progress and prospects for fertility preservation in prepubertal boys with cancer Vrije Universiteit Brussel
PURPOSE OF REVIEW: In the past few years, options for fertility preservation in prepubescent boys have enlarged tremendously.
RECENT FINDINGS: After a long period of studies on spermatogonial stem cell (SSC) transplantation in mice, recently successful use of rhesus monkey SSCs for autologous and allogeneic transplantation was demonstrated. Furthermore, newer protocols on transplantation of SSCs back into the testes and on how to ...
The use of dried blood spots for quantification of 15 antipsychotics and 7 metabolites with ultra-high performance liquid chromatography - tandem mass spectrometry Vrije Universiteit Brussel University of Antwerp Ghent University
Therapeutic drug monitoring of antipsychotics is important in optimizing individual therapy. In psychiatric populations, classical venous blood sampling is experienced as frightening. Interest in alternative techniques, like dried blood spots (DBS), has consequently increased. A fast and easy to perform DBS method for quantification of 16 antipsychotics (amisulpride, aripiprazole, asenapine, bromperidol, clozapine, haloperidol, iloperidone, ...