3D dynamic super-resolution imaging of bacterial lysis KU Leuven
Fluorescence microscopy allows researchers to observe dynamic processes in live-cells. Unfortunately, the size of bacterial cells (~2μm) is close to the resolving power of an optical microscope, known as the diffraction-limit. Therefore, while the general shape of bacteria can be seen, their sub-cellular details cannot be resolved. Particularly, observing the effects of antibiotic treatment on live bacteria is strongly obscured by the ...