Projects
Unraveling the trichothecene degradation pathway for valorization in pre- and post-harvest remediation Ghent University
Mycotoxins are toxic molecules produced by fungi which can contaminate crops on the field as well as food and feed stocks during storage. Consuming contaminated food or feed is harmful to both humans and animals. To combat this issue, farmers and feed pro
Characterization and engineering of a polysaccharide mono-oxygenase involved in the degradation of (ligno) cellulosic biomass Ghent University
Lignocellulosic biomass is believed to be the most promising renewable feedstock for sustainable production of biofuels and commodity chemicals in biorefineries. While the need for sustainable systems is continuously increasing, the depolymerization of lignocellulose is impeded by its high recalcitrance. This makes the development of a cost-effective process extremely challenging. In enzymatic degradation, the classical view of synergistic ...
Diversity oriented synthesis based on the brevianamide scaffold for the development of physiologically active compounds Ghent University
The diketopiperazine scaffold is a preferred (sub)structure in a wide variety of physiologically active natural compounds, including brevianamide F (antibacterial), present in Streptomyces and Aspergillus species. The project aims at the synthesis of heterodiketopiperazine analogues with a less complicated structure than the active natural compounds or the synthesis of diketopiperazines with medicinal relevant substituents starting from amino ...