Projects
Robust statistical inference for the chain-ladder method KU Leuven
Stochastic claims reserving in non-life insurance is a major actuarial issue and there is a growing awareness that modern statistical techniques should be used when calculating the overall outstanding claims reserve (i.e. the money that a company should set aside). A very broad literature is available concerning deterministic and stochastic models for forecasting future claims. To model the uncertainty of these claims reserves estimates, the ...
Statistical and computational approaches to enable real-time phylodynamic inference KU Leuven
The current wealth of sequence data for most important infectious diseases is stretching current computational approaches, such as phylodynamic inference, to their practical limits. This project aims to develop statistical and computational approaches to extract timely epidemiological and evolutionary information from virus genome sequences during an ongoing epidemic. Reconstructing pathogen spread from genetic data as they become available ...
Processing of personal data regarding ethnic origin and disability for statistical purposes to combat discrimination. Vrije Universiteit Brussel
Adjoint-based shape optimization of the ITER divertor using advanced fluid neutral models KU Leuven
The extremely high heat fluxes exhausted onto the plasma-facing components of magnetically confined fusion devices pose a fundamental challenge for the design of a viable nuclear fusion power plant. Neutral particles play an essential role in mitigating these heat loads, and they must therefore be simulated accurately in plasma boundary codes. However, the accurate simulation of these neutral particles is a computational challenge. This work ...
Joint model-based registration and segmentation strategies for integrated quantitative analysis of cardiac MRI sequences KU Leuven
Cardiac magnetic resonance imaging (MRI) is a state-of-the-art method for non-invasive visualization and functional analysis of the heart and enables not only qualitative but also quantitative analysis. Examples are cine MRI for assessment of cardiac contraction or T1 mapping for quantitative characterization of myocardial tissue. The different images result in a large amount of data and provide complementary information to assess cardiac ...
Biomechanical Models of Cells during C. elegans Embryogenesis KU Leuven
The nematode C. elegans is widely used as a model organism to study embryonic development with the prospect to uncover conserved developmental mechanisms common to various animals. In spite of intensive research in this area, many observed cellular behaviors remain poorly explained, such as the reliable and nearly invariant cellular motions: How do cells find their correct positions in the embryo? Which positional cues do the cells follow? ...
Actuaries and STatisticians endeavour to design innovative, inclusive insurance products in a changing RISK landscape KU Leuven
Actuaries design and value risk transfers by analyzing insurance data sets with a sophisticated statistical
toolbox. Current practice faces technical challenges in the design and estimation of risk models from finegrained
data. At the same time, trust in modern-day insurance is under pressure. Policyholders and regulators
expect value creation from the collected granular data in the form of better insurance products and a ...
Development of a methodology for predicting the acousticperformance of built-up wall and floor systems at high frequencies KU Leuven
Lightweight systems such as cross-laminated timber elements, sandwich panels, gypsum board walls,... are emerging in building construction. Because of their relatively low weight and complex vibro-acoustic behaviour, achieving a sufficient level of sound insulation with such systems is however challenging. The aim of this research is to develop a sound transmission loss prediction method, which exhibits similar accuracy as a comparable ...
Robust design optimization of three-dimensional concrete building components. KU Leuven
In engineering practice, structures are typically designed to have a minimal weight or cost, while satisfying all safety and serviceability constraints. These constraints can for example be the load-bearing capacity or deflection of a structure, or limiting the amount of damage or stress in the structure.
In general, the design of structures follows either a performance-based or a code-based approach. With performance-based design, ...