The role of adipose tissue in ICU-acquired weakness KU Leuven
Prolonged critically ill patients frequently develop muscle wasting and weakness of limb and respiratory muscles, termed critical illness-induced or intensive care unit (ICU)-acquired weakness. Mechanisms underlying this debilitating condition are complex, affecting both muscles and nerves. Whereas hypercatabolism in these patients induces loss of muscle mass, counterintuitively, adipose tissue is preserved or even increased during prolonged ...