Projects
High Resolution Inductive Coupled Plasma Mass Spectrometer (HR-ICP-MS). University of Antwerp
Ion mobility high resolution mass spectrometer: a strong tool for fragile structures. University of Antwerp
Development and theoretical models fot the determination of absolute configuration of chiral molecules: new approaches based on a second generation dual PEM vibrational circular dichroism specttrometer Ghent University
The newest generation of spectrometers for vibrational circular dichroism (vcd) allow an important reduction of signal/noise ratio's. This allows extending VCD to matrix isolation studies and the development of new algorithms for VCD calculations.
Study of induced matrix elements in beta decay with a multiwire drift chamber based spectometer KU Leuven
MALDI Mass Spectrometry Imaging (MALDI-MSI): Bridging proteomics and imaging. University of Antwerp
Data Independent Acquisition Mass Spectrometry to Mine Human Stem Cell Histone Epigenetics Ghent University
Epigenetic modifications are essential in the regulation of many biological processes. The histone proteins that are intimately associated with DNA to form the chromatin are pivotal substrates herein. Here, we will apply bottom-up mass spectrometry data independent acquisition strategies to map thousands of PTM in a quantitative manner and to generate a first birdU+2019s eye view of the so-called U+201Chistone codeU+201D.
Suspect screening and Target workflows using multi-dimensional chromatography and mass spectrometrY to investigate human eXposure to emerging contaminants by wastewater analysis (STYX). University of Antwerp
Pandemic preparedness: developing a multiplexed mass spectrometry assay to screen for pathogens and the induced immune response. Ghent University
The SARS-CoV-2 pandemic has abruptly illustrated the lack of pandemic preparedness. Therefore, health organisations as the WHO have recommended the development of a robust molecular screening platform for early detection and monitoring of the spread of pathogens through the population. This implies supplementing current diagnostic tests like nucleic acid amplification tests (NAATs) with tests targeting other biomolecules, like proteins. ...