Functional Human HEPatocytes, stellate cells and sinusoidal endothelial cells from STEMcells Ghent University
The overarching goal of HEPSTEM is to develop from human pluripotent stem cells (embryonic stem cells (hESC) and induced pluripotent stem cell (hiPSC)) mature, functional hepatocytes. Such cells could be used
(1) by the pharmaceutical industry to evaluate drug metabolism; study mechanisms underlying HBV/HCV infections and develop antiviral therapies,
(2) in bioartifical liver (BAL) devices that can support detoxification functions ...