Decoding the non-folding code of preproteins secretion during Sec translocase targeting and secretion KU Leuven
The Sec secretion system is the general and essential protein export pathway across life. Its central component is the Sec translocase, a nanomachine that recognizes exported proteins and takes them out of cell membranes. Pathogenic bacteria use the Sec system to export proteins such as toxins. To control pathogenicity and exploit it for biopharmaceuticals production we need to understand how it works. Scientists have identified Sec ...