Projects
Efficacy of offering a self-sampling device by the GP to reach women underscreened in the routine cervical cancer screening programme compared to sending reminder letters by the screening organization (ESSAG trial) Vrije Universiteit Brussel
Beyond transplantation: Combining high throughput and virtual drug screening to develop an innovative eye drop for corneal endothelial regeneration. University of Antwerp
Suspect screening and Target workflows using multi-dimensional chromatography and mass spectrometrY to investigate human eXposure to emerging contaminants by wastewater analysis (STYX). University of Antwerp
Genetic risk stratification in familial idiopathic pulmonary fibrosis to refine the multimodal screening program for relatives KU Leuven
Idiopathic pulmonary fibrosis (IPF) is the most common form of interstitial lung disease. The increased burden of IPF within families, familial pulmonary fibrosis (FPF) indicates that genetic factors are important in the risk of developing IPF. To date, a number of common and rare genetic variants contributing to the risk of pulmonary fibrosis have been identified. However, the majority of these genetic risk factors still remain unknown. ...
Reaching more women in cervical cancer screening with a better prediction of their cancer risk. University of Antwerp
Development of an innovative multiparameter sensing platform based on integrated impedance and thermal sensors for the screening of interface phenomena and changes in bulk liquid for lab-on-chip applications. Hasselt University
Developing a combined screening and molecular triage approach for cervical cancer based on HPV detection, quantification, genotyping and DNA methylation in self-samples. University of Antwerp
Deciphering persister awakening in uropathogenic Escherichia coli through CRISPRi screening KU Leuven
Urinary tract infections (UTIs) are a worldwide health concern and are mainly caused by uropathogenic Escherichia coli (UPEC). Antibiotic therapy failure and the chronic nature of UTIs can be attributed to a small fraction of transiently non-growing, antibiotic-tolerant cells called persisters. An innovative method to cure chronic UTIs would be to induce growth resumption in UPEC persisters, thereby re-sensitizing them to conventional ...
A Tumor Immune Micro Environment (TIME)-on-chip: an in vitro model for immuno-oncology and immunotherapy screening KU Leuven
The tumor immune microenvironment (TIME) plays an important role in cancer development, progression, and response to therapy. The microenvironment can elicit pro- or anti-tumoral responses, depending on the cellular and non-cellular components involved in it. Cancer immunotherapy, which mobilizes the body’s immune system to fight cancer, has been proven to be both effective and unsuccessful in a clinical setting, depending on the nature of ...