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Day-to-day egg count fluctuation in Schistosoma mansoni infection and its operational implications Institute of Tropical Medicine
In a study group of 183 people in a Schistosoma mansoni-endemic area in Burundi, stool examinations were performed with duplicate 25-mg Kato-Katz slides on seven occasions (days 1, 3, 5, 8, 10, 32, and 37). Point prevalences detected by single examinations of 25 mg and 50 mg of stool varied from 41.0% to 57.9% and from 55.7% to 63.9%, respectively. The cumulative prevalence for all seven measurements was 82.0%. The individual day-to-day ...
Analysis of worm burden variation in human Schistosoma mansoni infections by determination of serum levels of circulating anodic antigen and circulating cathodic antigen Institute of Tropical Medicine
Serum circulating anodic antigen (CAA) and circulating cathodic antigen (CCA) concentrations, as a possible direct measure of worm burden, were compared with fecal egg counts in a heavily Schistosoma mansoni-infected population from Zaire to allow differentiation between worm loads and worm fecundity in relation to age and intensity of infection. Of the 517 subjects, 95% excreted eggs and 97% demonstrated circulating antigens. Fecal egg counts ...
Repeated community-based chemotherapy for the control of Schistosoma mansoni: effect of screening and selective treatment on prevalences and intensities of infection Institute of Tropical Medicine
The impact of repeated selective chemotherapy on prevalences and intensities of infection with Schistosoma mansoni was evaluated in Gihungwe Transversals 1 and 2 (initial prevalence 60%) and Buhandagaza/Kizina (initial prevalence 35%), two village clusters in Burundi. Surveys were carried out at months -6, -3, 0, 3, 6, 9, 12, 24, and 36, with reference to the first intervention; treatment with praziquantel (40 mg/kg) was given at months 0, 12, ...
The distribution of Schistosoma mansoni in the Rusizi Plain (Burundi) Institute of Tropical Medicine
A regional survey of Schistosoma mansoni infection has been performed in the Rusizi Plain (Burundi), on a geographically evenly distributed 5% population sample (6203 subjects) in 41 localities. The overall prevalence was 33%, with 58% of the cases excreting less than 100 eggs per gram of faeces and a mean egg load of positives of 98 eggs per gram. The geographical distribution is very focal; local prevalences range from 3% to 63%, but vary also ...
Side effects of praziquantel in the treatment of Schistosoma mansoni in Maniema, Zaire Institute of Tropical Medicine
In a small community in Maniema, Zaire, heavily infected with Schistosoma mansoni, direct observations were made of the side effects of praziquantel in the hours immediately after treatment. Intense abdominal discomfort and the production of bloody diarrhoea were observed in more than half of the treated population. These effects were seen both in children and in adults and the onset of the symptoms was registered within 30 min of treatment. The ...
Diagnostic Issues of Acute Schistosomiasis With Schistosoma mekongi in a Traveler: A Case Report KU Leuven
A Belgian traveler returning from Laos developed acute schistosomiasis. Feces microscopy and polymerase chain reaction (PCR) followed by sequence analysis revealed Schistosoma mekongi. Schistosome antibody test results and real-time PCR in serum were initially negative or not interpretable. A HRP-2 antigen test for Plasmodium falciparum and an enzyme-linked immunosorbent assay (ELISA) antibody test for Trichinella yielded false-positive results.
Currently available monitoring and surveillance systems for Taenia spp., Echinococcus spp., Schistosoma spp., and soil-transmitted helminths at the control/elimination stage : a systematic review Ghent University
An increasing global focus on neglected tropical diseases (NTDs) has resulted in the set up of numerous control and elimination activities worldwide. This is partly true for Taenia solium taeniasis/cysticercosis, the most important foodborne parasitic infection. Despite substantial progress, adequate monitoring and surveillance (M&S) are required to sustain a status of control/elimination. This is often lacking, especially for T. solium. ...