1 - 10 of 269 results
A novel electrochemical microreactor for the synthesis of fine chemicals KU Leuven
Chemical synthesis routes towards 3-dimensional metal oxide nano-architectures for energy generation and storage Hasselt University
Computational investigations of the catalytic mechanism of Staphylococcus aureus transglycosylase: design and chemical synthesis of novel mechanism-based inhibitors. University of Antwerp
Isolation, structure elucidation and chemical synthesis of compounds with hypoglycemic activity from Gynura divaricata and G. bicolor Ghent University
Gynura divaricata and G. bicolor are two plants that are used in traditional Chinese medicine for the treatment of diabetes. In this project their hypoglycemic activity is investigated in pharmacological studies. Afterwards, attempts will be undertaken to isolate the active compounds and their derivatives.
Development of methods for enrichment and analysis for trace analysis of endocrine disrupting chemicals in water samples mediated by synthetic selective receptors Ghent University
A method will be developped allowing sorptive extraction of EDC's from contaminated water samples, based on immobilized peptidomimetics mimicking the estrogen receptor recognized by EDC's. Using smart thermoresponive polymers as solid support should pave the way to selective chromatographic analytical methods for determining EDC's.
Synthesis of diamino acid derivatives with a cyclopropane or aziridine skeleton and their application in the synthesis of potential physiologically active alpha, gamma-dimainobutyric acid derivatives Ghent University
The synthesis of constrained x, B- or x, Y-diamino acid derivatives as building blocks for new substituted 2,4-diaminobutyric acid derivatives is of great importance in medicinal and agricultural chemistry. This research concerns the development of stereoselective syntheses and biochemical evaluation of new derivatives of 1,2-diaminocyclopropane-1-carboxylic acid, 2-amino-2-aziridin-2-ylacetic acid and 2-amino-3-aziridin-2-ylpropionic acid ...
Visible-light photoredox catalysis: synthesis of sulfonylated heterocycles via thiosulfonates. University of Antwerp
Synthesis and application of probes for serine and cysteine hydrolases and the polyamine transport system KU Leuven
Activity-based probes (ABPs) are small molecular tools that allow the detection and monitoring of enzyme activity by covalently binding onto the active site of the enzyme. They consist of a warhead that binds the enzyme, a recognition element that alters the selectivity of the probe and a detection tag that allows the visualization, quantification or purification of probe-labeled enzymes. ABPs are applied to elucidate enzyme function, enzyme ...
Multiscale modeling of complex kinetics on metal surfaces: Fischer-Tropsch Synthesis Ghent University
Fischer-Tropsch synthesis offers the possibility to convert coal, natural gas or biomass to high-quality fuels or base chemicals. Complete control of the process is, however, only possible when the complex kinetics that take place on the metal surface are unraveled.