Publications
Loss of susceptibility, an underexplored approach for durable resistance to plant-parasitic nematodes Ghent University
Validation of three MicroScan (R) antimicrobial susceptibility testing plates designed for low-resource settings Institute of Tropical Medicine
Easy and robust antimicrobial susceptibility testing (AST) methods are essential in clinical bacteriology laboratories (CBL) in low-resource settings (LRS). We evaluated the Beckman Coulter MicroScan lyophilized broth microdilution panel designed to support Médecins Sans Frontières (MSF) CBL activity in difficult settings, in particular with the Mini-Lab. We evaluated the custom-designed MSF MicroScan Gram-pos microplate (MICPOS1) for ...
Antimicrobial susceptibility testing of Eggerthella lenta blood culture isolates at a University Hospital in Belgium from 2004 to 2018 Vrije Universiteit Brussel
OBJECTIVES: Eggerthella lenta is a Gram-positive anaerobic bacillus that is an important cause of bloodstream infections. This study aims to test the susceptibility of Eggerthella lenta blood culture isolates to commonly used antibiotics for the empirical treatment of anaerobic infections.
METHODS: In total, 49 positive blood cultures for Eggerthella lenta were retrospectively included from patients hospitalised at the Universitair ...
Comparison of Two Commercial Colorimetric Broth Microdilution Tests for Candida Susceptibility Testing Vrije Universiteit Brussel KU Leuven
Two colorimetric broth microdilution antifungal susceptibility tests were compared, Sensititre YeastOne and MICRONAUT-AM for nine antifungal agents. One hundred clinical Candida isolates were tested, representing a realistic population for susceptibility testing in daily practice. The reproducibility characteristics were comparable. Only for fluconazole, caspofungin, 5-flucytosine and amphotericin B, an essential agreement of ≥90% could be ...
Legionella antibiotic susceptibility testing Vrije Universiteit Brussel
Legionella pneumophila, a Gram-negative bacillus, is the causative agent of Legionnaire's disease, a form of severe community-acquired pneumonia. Infection can have high morbidity, with a high proportion of patients requiring ICU admission, and up to 10% mortality, which is exacerbated by the lack of efficacy of typical empirical antibiotic therapy against Legionella spp. The fastidious nature of the entire Legionellaceae family historically ...
Antimicrobial susceptibility monitoring of Mycoplasma hyopneumoniae isolated from seven European countries during 2015-2016 Ghent University
Model system parameters influence the sodium hypochlorite susceptibility of endodontic biofilms Ghent University
Can previous associations of single nucleotide polymorphisms in the TLR2, NOD1, CXCR5, and IL10 genes in the susceptibility to and severity of Chlamydia trachomatis infections be confirmed? Institute of Tropical Medicine
Clear inter-individual differences exist in the response to C. trachomatis (CT) infections and reproductive tract complications in women. Host genetic variation like single nucleotide polymorphisms (SNPs) have been associated with differences in response to CT infection, and SNPs might be used as a genetic component in a tubal-pathology predicting algorithm. Our aim was to confirm the role of four genes by investigating proven associated SNPs ...
Repeated disinfectant use in broiler houses and pig nursery units does not affect disinfectant and antibiotic susceptibility in Escherichia coli field isolates Research Institute for Agriculture, Fisheries and Food Ghent University
BACKGROUND: Disinfectants are frequently used in animal production to reduce or eliminate the load of infectious agents and parasites in buildings and equipment associated with the housing or transportation of animals. There are growing concerns that the use of disinfectants would select for resistance to antibiotics and disinfectants. The aim of this study was to determine the effect of repeated use of different disinfectants on the ...