APLP2 regulates neuronal stem cell differentiation during cortical development KU Leuven
Human amyloid precursor protein (APP) belongs to a gene family that codes for type I trans-membrane proteins in different species, including fruit flies, roundworms and mice. Amyloid Precursor-like Protein1 and 2 (APLP1 and APLP2) are the two other mammalian members of this gene family. Like APP, APLP1 and APLP2 are transmembrane proteins with a large extracellular N-terminal domain and short cytoplasmic C-terminal fragment. Another ...