Structural and functional evolution of a pheromone defense system in Amphibia. Vrije Universiteit Brussel
Proteins can undergo a diversification of functions by means of duplication events and neofunctionalisation. Sodefrin Precursor Factor (SPF) is a protein so far described only in salamanders, which has two pheromone functions. We propose here the hypothesis of an SPF diversification of pheromone and defensive functions. To unravel structural and functional evolution of SPF in amphibians, new precursors are first identified using ...