Projects
Using ‘real-world’ data to gain knowledge on medication safety during pregnancy: towards a ‘fit-for-purpose’ registration system on maternal medication use and mother-infant outcomes (BELpREG). KU Leuven
Microbiological safety cabinets: key equipment for veterinary microbiology research Ghent University
Microbiological safety cabinets are indispensable for the study of bacterial and mycotic infections in animals. This application describes the replacement of the current, outdated cabinets to keep compliant with safety regulations concerning infectious agents. This infrastructure is essential for the daily research activities within the department, and that in collaboration with other partners (within and outside UGent).
GEAR: Brussels Liver Research to Valorisation Alliance (B-Liver): Valorisation of VUB’s liver cell biology and toxicology expertise via a consortium focused on liver therapeutics, patient and consumer safety. Vrije Universiteit Brussel
Validation of autophagy induction as a therapeutic strategy: from drug discovery and preclinical evaluation to safety investigation and biomarker research. University of Antwerp
Zebrafish platform for drug discovery and safety testing KU Leuven
The academic research activities of the Laboratory for Molecular Biodiscovery are focused on generating tailor-made zebrafish models of human diseases and zebrafish toxicity reporter lines with high valorisation potential. In a first valorization trajectory zebrafish models of human diseases (with an unmet clinical need) are used to discover novel lead compounds from libraries accessible via KU Leuven / EU-project partners / or industrial ...
KU Leuven Stem Cell Platform KU Leuven
Insufficient drug safety and lack of efficacy are the main reasons for the high failure rate of molecules in clinical development. The use of patient−derived, human cell systems in preclinical research holds the promise of leading to more efficacious and safer drugs, thus reducing ‘attrition’ and its associated costs in drug development. KU Leuven Stem Cell Platform (KUL−STEM) will develop state and beyond state of the art technologies that ...
Platform for mycotoxin technologies and diagnostics (MYCO-TECH) Ghent University
Mycotoxins are poisonous fungal metabolites, causing economic losses through food/feed contamination, and exerting health threats to human and animals through dietary consumption on a global scale. Recent studies have shown that 50% of all crops wordwide are contaminated with mycotoxins exceeding the maximum allowed limits. Additionally, climate change is worsening the mycotoxin issue. Therefore, high-quality, high-throughput and innovative ...
Salmonella and E. coli in poultry production systems in Kenya: Investigating antimicrobial use, resistome profiling and interventions for improvement of poultry production and human health. Ghent University
Kenya’s poultry industry is linked to transmission of antimicrobial resistance genes and resistant pathogens between animals and humans. Despite existing policies for food safety, sustainable interventions applicable to different poultry production systems are lacking. This study will evaluate prevalence of AMR in E. coli and Salmonella, antimicrobial use and risk factors, and model utility of potential interventions in different production ...