Identifying genes and molecular mechanisms contributing to mutational robustness in Saccharomyces cerevisiae. KU Leuven
Organisms require mutations to evolve, but only a fraction of mutations is potentially beneficial. Therefore, organisms need to protect themselves from the deleterious effects of mutations. Some biological mechanisms can prevent the occurrence of mutations, but they also restrict an organism’s ability to evolve. Recent studies have shown that the effect of deleterious mutations can be hidden under normal circumstances. However, major ...