Rifampicin drug resistance tests for tuberculosis: challenging the gold standard Institute of Tropical Medicine
The nitrate reductase assay for the rapid detection of isoniazid and rifampicin resistance in Mycobacterium tuberculosis: a systematic review and meta-analysis Ghent University Institute of Tropical Medicine
Investigation of rifampicin resistance mechanisms in Brucella abortus using MS-driven comparative proteomics Ghent University
Variable ability of rapid tests to detect Mycobacterium tuberculosis rpoB mutations conferring phenotypically occult rifampicin resistance Institute of Tropical Medicine
We compared the ability of commercial and non-commercial, phenotypic and genotypic rapid drug susceptibility tests (DSTs) to detect rifampicin resistance (RR)-conferring 'disputed' mutations frequently missed by Mycobacterium Growth Indicator Tube (MGIT), namely L430P, D435Y, L452P, and I491F. Strains with mutation S450L served as positive control while wild-types were used as negative control. Of the 38 mutant strains, 5.7% were classified ...
Nevirapine pharmacokinetics when initiated at 200 mg or 400 mg daily in HIV-1 and tuberculosis co-infected Ugandan adults on rifampicin University of Antwerp Institute of Tropical Medicine
How should discordance between molecular and growth-based assays for rifampicin resistance be investigated? University of Antwerp Institute of Tropical Medicine
Disputed rpoB mutations can frequently cause important rifampicin resistance among new tuberculosis patients University of Antwerp Institute of Tropical Medicine
Extension of the intensive phase reduces relapse but not failure in a regimen with rifampicin throughout University of Antwerp Institute of Tropical Medicine
Twenty years of rifampicin resistance surveillance in Bangladesh: periodic vs. continuous monitoring Institute of Tropical Medicine
OBJECTIVE: To analyse 20 years of tuberculosis (TB) drug resistance surveillance, comparing conventional periodic random drug resistance surveys with continuous monitoring, in Damien Foundation-supported districts of Bangladesh.
DESIGN: Retrospective study of data on TB drug resistance from five periodic surveys among newly registered patients vs. continuous monitoring of retreatment patients from 1996 to 2016.
RESULTS: Periodic ...