Projects
Use of stereolithographic model in tooth autotransplantation and periodontal ligament stem cells for pulp revascularization and reinnervation to increase the success rate for tooth replacement in children KU Leuven
Loss of permanent teeth is a particular challenge in children considering that alveolar bone growth is not yet complete and treatment approaches should adapt to both growth and developmental changes in the oral region to have the potential for long-term survival. This could be realized via autotransplantation, which is a biological approach for tooth replacement in young children. Key factor for its success is the preservation of the ...
Use of stereolithographic model in tooth autotransplantation and periodontal ligament stem cells for pulp revascularization and reinnervation to increase the success rate for tooth replacement in children Hasselt University
Innovative scaffolds with enhanced vascularization and patterned cells for bone tissue engineering Ghent University
Tissue engineering (TE) is a promising research field to address the loss or failure of organs/tissues. However, designing larger performant TE constructs is challenging due to the need for (1) functional scaffold vascularization in combination with (2) controlled cellular distribution. Therefore, this project aims to develop a new strategy to synthesize vascularized TE bone constructs, as bone is a very relevant tissue. The construct will ...
Fundamental understandings and development of a novel plasma biofunctionalized 3D-printed/electrospun scaffold for synergetic vascularization and regeneration of spinal cord hemisection Ghent University
More than half a century has passed since the first attempts to repair the devastating spinal cord injuries (SCI). To date, no satisfying clinical outcome is achieved given the defect complexity hampering regeneration. Current tissue engineering strategies promoting nerve growth only show weak neurological recovery. This project launches therefore a novel combinatorial approach through the design of a scaffold synergistically targeting ...
Towards an improved dental pulp-capping therapy KU Leuven
SUMMARY.
A recent Delphi survey on the future of restorative dentistry for the next 20 years identified maintenance of the pulp vitality as of the highest importance [1]. The authors rated bioactivity toward the pulp-dentin complex as key property for future tooth-restorative materials. This need to develop bioactive restorative materials was also the conclusion drawn on a workshop ("Future innovation and research in dental restorative ...