Projects
The natural K, Fe, and Cu isotopic response to Pt-based chemotherapeutic drug resistance in ovarian cancer Ghent University
Cancer is the second leading cause of death globally and in the EU, and was responsible for an estimated one in six deaths in 2018. Early diagnosis plays an important role in determining cancer treatment outcomes, but the diagnosis of ovarian cancer poses significant challenges; the routine screening of asymptomatic average-risk women is not recommended by any professional society. Chemotherapy using Pt-based compounds (e.g. carboplatin, ...
Defining the role of the tumor microenvironment in treatment resistance of OVArian cancer through patient-Derived EXplants (OVADEX) KU Leuven
Treatment resistance in ovarian cancer (OC) is common. Recent efforts have identified new treatment approaches with potential to improve its management, but their therapeutic effects are limited due to treatment resistances.
Tumor microenvironment (TME) is emerging as a key contributor to treatment resistance, being the metabolic cross-talk between TME and OC one of the recently proposed mechanisms. The hosting lab has evidence that ...
Tracking epigenetic plasticity in circulating tumor-derived DNA to monitor drug resistance and guide personalized treatment in cancer patients Ghent University
Tracking epigenetic plasticity in circulating tumor-derived DNA to monitor drug resistance and guide personalized treatment in cancer patients Flanders Institute for Biotechnology
Enhanced Networking on Antimicrobial Resistance Surveillance with Next Generation Sequencing (AmReSu). University of Antwerp
Understanding resistance to immune checkpoint inhibitors by mapping the tumor-host ecosystem at single-cell resolution — cellsIMPACT - marie curie individual fellowship Joanna Pozniak Flanders Institute for Biotechnology
RESISTANCE UNDER COMBINATORIAL TREATMENT IN ER+ AND ER- BREAST CANCER.’ — ‘RESCUER’ Flanders Institute for Biotechnology
The value of diagnostics to combat antimicrobial resistance by optimising antibiotic use (VALUE-Dx). University of Antwerp
Disseminating Innovative Solutions for Antibiotic Resistance Management - DISARM Ghent University
The DISARM thematic network (Disseminating Innovative Solutions for Antibiotic Resistance Management) is focused on disseminating best practices from innovative farms and research on how to reduce antibiotic resistance in livestock farming. Antibiotic resistance management is not only important to farming, it can also lead to reduced effectiveness of antibiotics in treating humans. Tackling antibiotic resistance is a major strategic ...