Projects
Novel insights in the definition and treatment of high risk and oligometastatic prostate cancer KU Leuven
There is an urgent need to develop novel treatment strategies in the management of high-risk prostate cancer. These patients have a significantly elevated risk of disease recurrence and progression resulting in worse prognosis. To this end, the first objective of this thesis was to investigate the efficacy and tolerability of a novel second-line anti-androgen, apalutamide, prior to radical prostatectomy in high-risk PCa patients. The ...
18F-PSMA-1007 PET/MR imaging, quantification and radiomics in the primary staging of prostate cancer and response prediction after neoadjuvant hormonal therapy KU Leuven
Prostate-specific membrane antigen (PSMA) is a cell-surface glycoprotein overexpressed on prostate cancer (PCa) cells. At present, PSMA PET is the gold standard to localize disease in patients with biochemically recurrent PCa and guides treatment in this clinical scenario. However, the role of PSMA PET in primary staging and its effect on patient management and outcome has only been studied in a limited number of mostly retrospective studies. ...