Projects
Respiratory Syncytial virus consortiem in Europe (RESCEU). University of Antwerp
Characterization of a contemporary Respiratory Syncytial Virus isolate for use in pre-clinical and clinical research (ReSVistrain). University of Antwerp
Unraveling direct interactions between the airway microbiota and respiratory syncytial virus. University of Antwerp
Respiratory Syncytial virus consortium in Europe (RESCEU). University of Antwerp
Lifting barriers towards obtaining actionable public health information from pathogen genomes: model advancement, performance evaluation and application to respiratory syncytial virus types A and B KU Leuven
Molecular epidemiology approaches can glean epidemiological information from pathogen genomes, and have grown into an important instrument across infectious disease research. Harnessing these methods for actionable information to public health -an important goal in e.g. HIV research- requires the ability to obtain timely and unbiased information on key epidemic processes such as migration. The adoption of model-based phylogenetic inference of ...
REspiratory Virus Repository ANTwerp (ReViRAnt). University of Antwerp
Respiratory Syncitial Virus immunology and molecular virology Ghent University
The ectodomain of the short hydrophobic protein (SHe) of Respiratory Syncytial virus will be used as a recombinant virus-like particle in prophylactic vaccination studies against this virus. The protective efficacy of SHe-specific adaptive immunity will be characterized in a mouse model. Using passive transfer of antisera and immune cells the mechanism of protection of this novel vaccine will be determined.
Optimize viral replication in primary human airway epithelial (HAE) cells for use in antiviral research to combat respiratory viral infections KU Leuven
This project focuses on exploring the use of HAE cultures to study the treatment of viral respiratory infections. HAE cultures will be used to evaluate novel antiviral strategies to combat Respiratory Syncytial Virus (RSV) infection and explore the kinetics of replication of different RSV virus strains. This will result in an optimized culture system to be used to characterize viral strains in a relevant ex vivo system and link viral factors ...