Projects
The effectiveness and cost-efficacy of different guidance methods to facilitate lifestyle changes in the treatment of NAFLD Hasselt University
Changing Tactics? Optimizing ECT in difficult-to-treat depression University of Antwerp
The role of motivation in return to work after work disability KU Leuven
Background: Motivation is a much-discussed topic in the context of work disability. The increasing number of long-term sickness is often linked to a lack of motivation by both policymakers and the general population. However, these are assumptions that have not been thoroughly investigated scientifically until now. This dissertation attempts to fill this gap. The research first maps to what extent motivation can be measured in the context of ...
Co-payments and the financial accessibility of medical care: an experimental investigation into the impact of lowering co-payments on patterns of medical consumption and unmet need. University of Antwerp
Pharmacometric models to improve therapeutic drug monitoring of monoclonal antibodies in the treatment of inflammatory bowel diseases KU Leuven
Inflammatory bowel diseases (IBD) are chronic, relapsing, inflammatory conditions of the gastrointestinal (GI) tract. Ulcerative colitis (UC) and Crohn’s disease (CD) are the primary subtypes of IBD. Although the etiology remains incompletely understood, it is generally accepted that IBD is the result of an inappropriate host response to environmental factors in genetically susceptible individuals. In Western Europe, prevalence of UC is ...
Analysis of policies regarding market access of oncology drugs. KU Leuven
Changing demographics, earlier detection and treatment of cancer and a growing number of therapeutic options and combination therapies lead to an increasing trend in expenditures on cancer medicines. Regulations for market access of cancer medicines, including marketing authorization, price setting and reimbursement, should ensure that effective and safe medicines are affordable for society, accessible for individual patients and profitable ...
Evidence-based conservative approach to idiopathic scoliosis during growth in everyday clinics KU Leuven
Conservative approach to idiopathic scoliosis is particularly challenging due to the not well-known natural history of the disease and the relative uncertainty on the efficacy of available treatments. Recently patients recruitment in a large Randomized Controlled Trial (RCT) on a high-risk population was stopped for ethical reasons due to the clear efficacy of bracing versus natural history, and this led to an increased worldwide attention ...
Kan langdurige intranasale oxytocine toediening prosociaal gedrag stimuleren bij autisme? Een combinatie van multimodale beeldvorming van de hersenen, oxytocinerge metingen en real-life sociale interactie paradigma's om subtiele interventie effecten te l KU Leuven
An in-depth investigation of neurovisceral integration and regulation in children with autism spectrum disorders. KU Leuven
Despite an increased interest in the role of social stress in the etiology of autism spectrum disorders (ASD), a set of neurodevelopmental disorders characterized by socio-communicative problems, disruptions in autonomic regulatory processes as well as their neural underpinnings remain poorly understood in ASD. Using a strong psychobiological framework (based on the Polyvagal Theory by Porges) and an extensive assessment protocol including ...