Predicting and treating non-typhoidal Salmonella bloodstream infection in children in sub-Saharan Africa KU Leuven
Non-typhoidal Salmonella (NTS) frequently cause, often fatal, bloodstream infections in children in sub-Saharan Africa. In this region, circulating NTS serotypes have genetically evolved towards more invasive and human-adapted phenotypes. Furthermore, sub-Saharan African children are susceptible to invasive NTS infections due to comorbidities impairing their immune system (Plasmodium falciparum (Pf) malaria, anemia, malnutrition, HIV). The ...