Publications
LC-MS analysis combined with principal component analysis and soft independent modelling by class analogy for a better detection of changes in N-glycosylation profiles of therapeutic glycoproteins Vrije Universiteit Brussel
Therapeutic proteins are among the top selling drugs in the pharmaceutical industry. More than 60 % of the approved therapeutic proteins are glycosylated. Nowadays, it is well accepted that changes in glycosylation may affect the safety and the efficacy of the therapeutic proteins. For this reason, it is important to characterize both the protein and the glycan structures. In this study, analytical and data processing methods were developed ...
Membrane bioreactor fouling behaviour assessment through principal component analysis and fuzzy clustering Ghent University
Development of skeletal kinetics mechanisms for plasma-assisted combustion via principal component analysis Vrije Universiteit Brussel
The positive effect of plasma discharges on ignition and flame stability motivates the development of detailed kinetic mechanisms for high-fidelity simulations of plasma-assisted combustion. Because of their hierarchical nature, combustion processes require a large number of chemical species and pathways to describe hydrocarbon oxidation. In order to simulate kinetic enhancement by non-thermal electrons, additional species and processes are ...