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Prenatal Neurologic Anomalies: Sonographic Diagnosis and Treatment KU Leuven
The low prevalence of fetal CNS anomalies results in a restricted level of exposure to, and limited experience for most obstetricians involved in, prenatal ultrasound. Sonographic guidelines for screening the fetal brain in a systematic way may increase the detection rate of fetal CNS anomalies, thus promoting correct referral to tertiary care centers offering patients a multidisciplinary approach to the condition. The aim of this review is to ...
Role of prenatal magnetic resonance imaging in fetuses with isolated mild or moderate ventriculomegaly in the era of neurosonography: international multicenter study KU Leuven
OBJECTIVES: To assess the role of fetal magnetic resonance imaging (MRI) in detecting associated anomalies in fetuses presenting with mild or moderate isolated ventriculomegaly (VM) undergoing multiplanar ultrasound evaluation of the fetal brain. METHODS: This was a multicenter, retrospective, cohort study involving 15 referral fetal medicine centers in Italy, the UK and Spain. Inclusion criteria were fetuses affected by isolated mild ...
Allo-immune thrombocytopaenia KU Leuven
This case report describes the prenatal diagnosis of an intracranial haemorrhage due to allo-immune thrombocytopaenia (AITP) with HPA-1b incompatibility. In this family, a previous child had died neonatally with a presumed diagnosis of schizencephaly. Severe open-lip schizencephaly can be difficult to differentiate from destructive brain lesions due to intracranial haemorrhage, but a correct diagnosis is important due to the high recurrence risk ...