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PROGNOSTIC FACTORS FOR OBSTETRIC AND ONCOLOGICAL OUTCOME IN PREGNANT WOMEN WITH CANCER Chemotherapy in pregnancy: from fetal safety to maternal efficacy KU Leuven
BACKGROUND The rarity of cancer and pregnancy hampering research, resulted in the arise of an International Network on cancer, Infertility and Pregnancy (INCIP). When cancer coincidences with pregnancy, the oncological and obstetric management is challenged by concerns on general health and prognosis of both the mother and the unborn child. Whenever possible, an oncological treatment plan according to the general standards of care for ...
Breast cancer (diagnosed) during pregnancy: Adapting recent advances in breast cancer care for pregnant patients KU Leuven
© Springer International Publishing AG 2017. Breast cancer during pregnancy (BCP), although rare, is increasing, and treatment should be as similar as possible to that for non-pregnant young breast cancer patients. A group of specialists convened to review current guidelines and provide guidance on how recent advances in breast cancer diagnosis and treatment can be adapted for pregnant patients. The majority of BCP patients will be considered ...
A dietary intervention to improve the microbiome composition of pregnant women with Crohn's disease and their offspring: The MELODY (Modulating Early Life Microbiome through Dietary Intervention in Pregnancy) trial design KU Leuven
Crohn's disease (CD), a type of inflammatory bowel disease (IBD), is a chronic condition of the gastrointestinal tract that is caused by the loss of mucosal tolerance towards the commensal bacteria resulting in inflammatory responses. It has long been postulated that the gut microbiota, a complex and dynamic population of microorganisms, plays a key role in the pathogenesis of IBD. Maternal diagnosis of IBD has been identified as the greatest ...
Views and preferences of medical professionals and pregnant women about a novel primary prevention intervention for hypertensive disorders of pregnancy: a qualitative study KU Leuven
BACKGROUND: Calcium and low-dose aspirin are two potential approaches for primary prevention of hypertensive disorders of pregnancy (HDP). This study aimed to explore the acceptability, views and preferences of pregnant women and primary healthcare providers for a fixed-dose combined preparation of aspirin and calcium (a polypill) as primary prevention of HDP in an unselected pregnant population. METHODS: In this qualitative study eight in-depth ...
Pertussis vaccination during pregnancy in Vietnam: Results of a randomized controlled trial Pertussis vaccination during pregnancy Hasselt University
A pertussis vaccination during pregnancy has recently been adopted in several countries to indirectly protect young infants. This study assessed the effect of adding a pertussis component to the tetanus vaccination, in the pregnancy immunization program in Vietnam. A randomized controlled trial was performed. Pregnant women received either a Tdap (tetanus, diphtheria acellular pertussis) vaccine or a tetanus only vaccine between 19 and 35 weeks' ...