Projects
A Nanopore Long-read Sequencing-based Approach to more Accurately Detect Predictive Biomarkers for Cancer Immunotherapy KU Leuven
In recent years, immune checkpoint inhibitors achieved remarkable clinical successes in several cancers. Quantifying the tumor’s total mutational load, assessing the expression of retrotransposable RNA and detection of CD8+ cytotoxic T-cells in tumors have all emerged as promising mechanisms underlying response to immune checkpoint inhibitors. However, in order to assess each of them as a potential biomarker for immune checkpoint inhibition, ...
Maternal antibodies as predictive biomarkers for Autism Spectrum Disorder Hasselt University
Peripheral blood monoicytes as potential predictive biomarkers for colorectal cancer diagnosis and progression. KU Leuven
Rationalizing the use of antimicrobial agents of critical importance for treating sepsis in domestic animals using predictive models, biomarkers and rapid microbial identification with MALDI-TOF MS Ghent University
To prevent resistance selection in humans and animals the use of critically important fluoroquinolones and cephalosporins in veterinary medicine needs to be restricted to the necessary minimum. Sepsis is by far the leading indication for these molecules. Despite legislation for cattle limiting the use of critically important antimicrobials, in practice there are several difficulties with the interpretation of terminology like 'urgency ...
Identification of clinical characteristics and biomarkers with a predictive value for conversion to dementia in patients with mild cognitive impairment. University of Antwerp
Overcoming intrinsic and acquired resistance to EGFR-targeting agents in cancer treatment: focus on identification of predictive biomarkers and novel therapeutic strategies. University of Antwerp
Overcoming intrinsic and acquired resistance to EGFR-targeting agents in cancer treatment: focus on identification of predictive biomarkers and novel therapeutic strategies. University of Antwerp
Carbon nanotube (CNT) induced epigenetic alterations -establishing potential predictive biomarkers for occupational health risks KU Leuven
Nanotechnology deals with the engineering of materials at the nanometer scale. At this size materials begin to exhibit unique properties that affect physical, chemical, and biological behavior and pose health/environmental hazard. Among other nanomaterials, carbon nanotubes (CNT) are of major concern owing to their similarity with asbestos and limited evidence of toxicity. The present study has therefore been designed to understand the ...