Projects
Fluorine-19 Magnetic Resonance Imaging as a Potential Tool in Preclinical Research --- With Focus on Diabetes KU Leuven
Diabetes remains one of the increasing threats to human health with over 422 million people suffering from the disease all over the world. Despite the advancements in understanding the disease and improvements in treatment, diagnosis and early prevention with effective monitoring of pre- and post- therapy of the disease is still urgently needed. Hereby, the function and mass of pancreatic islets (PIs) and in particular their beta cells play ...
Interventional X-ray system equipped with 3D rotational angiography for cardiovascular research in preclinical large animal models. KU Leuven
Current strategies for early treatment of acute coronary
syndromes (i.e. heart attacks) have improved acute survival
but subsequent heart failure and arrhythmias (sudden
cardiac death) are the long-term cause of mortality and
morbidity. Responsible use of large animals as preclinical
translational models remains a cornerstone in
cardiovascular research
and play an irrefutable role in exploratory and ...
Translational Molecular Imaging Program for the University of Antwerp: application driven preclinical research. University of Antwerp
Development and validation of optical imaging tools for advanced preclinical cancer research KU Leuven
The main aim of the current project lies in the development of a novel in vivo preclinical imaging system that allows researchers to study in a non-invasive manner interesting oncology-related parameters as a function of time at an unprecedented sensitivity. To reach this goal, a recently established imaging method called Aka-BLI will be used, in combination with existing probes to enable a rapid and cost-efficient method for high-throughput ...
Chicken chorioallantoic membrane (CAM) model as a research tool complementary to patient-derived xenografts (PDX) for preclinical drug testing in sarcomas. KU Leuven
Validation of autophagy induction as a therapeutic strategy: from drug discovery and preclinical evaluation to safety investigation and biomarker research. University of Antwerp
A preclinical research platform for Alzheimer's disease in the eye. KU Leuven
While Alzheimer's disease is the most prevalent neurodegenerative disease worldwide and despite decades of research, there is currently no therapy for it. Reasons for this treatment gap include the incomplete understanding of the complexity of pathological processes that underlie Alzheimer's disease, and the many hurdles between drug discovery and approval. In this project, we aim to address these needs via Alzheimer's research in the eye. ...