Polygenic risk scores for Alzheimer’s disease prediction and stratification KU Leuven
Alzheimer’s Disease (AD) is a neurodegenerative disease characterized by the accumulation of abnormal protein aggregates in the brain, i.e. amyloid (Aβ) plaques and tau tangles. AD is the most frequent cause of dementia, with over 40 million people affected worldwide. In its final phase, progressive loss of neurons impairs memory, cognition, and other functions depending on the affected brain areas. There is currently no treatment that stops ...