Artificial Lithographic MODel for COrNeal drug Screening (AL MOD CONS). University of Antwerp
Vienna University of Technology, Univerty of Lille, Catholic University of Louvain, Ghent University, Translational Neurosciences (TNW)
The cornea is the transparent window to the eye and as such, eye drops are an interesting route of drug administration. In this project, we propose the development of a 3D corneal cell model that can be used to investigate corneal drug interaction. Studies that aim to simulate the pharmacokinetics and toxicological properties of drugs are mainly based on oversimplified 2D monocultures or animal studies that suffer from interspecies differences. ...