DNA repair enzyme genotypes and their toxicologically relevant phenotypes Vrije Universiteit Brussel
A comprehensive review of studies of polymorphisms in DNA repair genes and associations with cancer risk was undertaken by Goode et al. [1]. In that study the authors concluded that published data were consistent with associations between: (a) the 8-oxoguanine-DNA glycosylase
(hOGG1) Ser326Cys variant genotype and increased risk of various types of cancer; (b) the X-ray repair cross-complementing group 1 (XRCC1) Arg194Trp variant genotype ...
(hOGG1) Ser326Cys variant genotype and increased risk of various types of cancer; (b) the X-ray repair cross-complementing group 1 (XRCC1) Arg194Trp variant genotype ...