BOF ZAP clinical pharmacology Ghent University
A professorship granted by the Special Research Fund is a primarily research-oriented position and is made available for excellent researchers with a high-quality research programme.
A professorship granted by the Special Research Fund is a primarily research-oriented position and is made available for excellent researchers with a high-quality research programme.
Scientific and technological progress has led to the development of innovative therapies, including advanced therapy medicinal products (ATMPs). These therapies offer new treatment options for serious, incurable diseases such as cancer and genetic disorders such as muscular dystrophy. Significant growth is expected in the number of ATMPs becoming available on the market. However, these ATMPs come at a very high cost, which puts pressure on ...
Drug development today is increasingly focused on the development of biological products, including advanced therapy medicinal products (ATMPs). However, market uptake of these therapies has been limited in Europe due to difficulties in obtaining reimbursement. Governments experience decision-uncertainty due to persisting uncertainties caused by shortcomings in clinical trial design and the unavailability of long-term data on efficacy and ...
Acquiring, further building and sharing of academic, scientific expertise with regard to the further development of a policy of best-value biological medicines, conducting academic, scientific research in this domain, mapping available research and resources for research and the concrete cooperation in the realization of a study that maps the motivation of the best-value choice of the prescription, the concerns of doctors and patients, the ...
Background and rationale: Pharmacometrics (mixed effects) modelling and simulation is increasingly used to characterise, understand, and predict the dose-exposure-response relationships of drugs. Consequently, model-informed drug development (MIDD) has become an established business value, facilitating a cost-efficient drug development process. Population-level dosing is the preferred dosage strategy, followed by group-level dosing ...
Inappropriate prescribing in older adults is regarded as a major and urgent healthcare problem. It has been associated with a substantial burden of iatrogenic morbidity, including adverse drug events. In particular older adults are regularly admitted to the hospital due to a multitude of drug-related problems, including the underuse of indicated therapies. A large part of these admissions is considered to be avoidable. After hospital ...
Rethinking access to medicines: towards a refined legal framework for medicine shortages